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STAT3 TRANSCRIPTION FACTOR
Descriptors Found:
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DeCS
Descriptor
English
:
STAT3 Transcription Factor
Descriptor
Spanish
:
Factor de Transcripción STAT3
Descriptor
Portuguese
:
Fator de Transcrição STAT3
Tree Number:
D12.644.360.024.342.300
D12.776.157.057.186.300
D12.776.476.024.421.300
D12.776.930.840.300
Definition
English
:
A signal transducer and activator of transcription that mediates cellular responses to
INTERLEUKIN-6
family
members. STAT3 is constitutively activated in a variety of TUMORS and is a major downstream transducer for the
CYTOKINE RECEPTOR GP130.
History Note
English
:
2006
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50796
Unique Identifier:
D050796
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS